Comparative Effectiveness Research

This web page will provide diabetes educators with information and resources on Comparative Effectiveness Research (CER) and Patient Centered Outcomes Research (PCOR).  Our goal is to keep you up-to-date on CER and PCOR related to diabetes care and to provide opportunities for you to learn more about this type of research. 

AADE Resources and Communications

External Links and Resources

Agency for Healthcare Research and Quality (AHRQ) - Effective Health Care Program

The Effective Health Care Program funds individual researchers, research centers, and academic organizations to work with the AHRQ to produce effectiveness and comparative effectiveness research (CER) for clinicians, consumers, and policy makers.  Resources include Research Summaries and Continuing Education activities.

The Autonomy Trial was a randomized trial that compared efficacy and safety of 2 algorithms for initiation and titration of prandial insulin lispro in people with type 2 diabetes who did not have adequate glycemic control using basal insulin plus oral medications.

Improving Your Office Testing Process: Toolkit for Rapid-Cycle Patient Safety and Quality Improvement provides steps to identify areas for improvement and strategies for doing so.

Endocrine Society - Patient Decision Aids

Managing diabetes often involves making decisions about treatment.  These decisions need to account for the patient perspective because it is the person with diabetes who is the one engaging in self-care.  Patient decision aids don’t recommend one treatment option over another, but rather are a way to provide patients with information so that they are prepared to work with their healthcare provider to make decisions about treatments that are right for them.

Is Mealtime Insulin Right? 
Setting Goals & Keeping Your Body Healthy 
Starting Mealtime Insulin
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Patient Centered Outcomes Research Institute (PCORI)

PCORI is an independent, non-profit organization authorized by Congress. PCORI's mission is to fund research that will provide patients, their caregivers, and clinicians with the evidence-based information needed to make better-informed health care decisions.

For those interested in learning more about how to incorporate patient reported outcomes into clinical care and electronic health records – the PCORI is holding an infrastructure workshop on November 19 -20  2013 which it is making available via webcast.



Comparative Effectiveness Research (CER) is a type of health care research that compares the results of one approach for managing a disease to the results of other approaches.  CER usually compares two or more types of treatment for the same disease.  CER is designed to inform health care decisions by providing evidence on the effectiveness, benefits, and harms of different treatment options. 

Patient Centered Outcomes Research (PCOR) helps people and their caregivers communicate and make informed health care decisions.  PCOR actively engages patients and key stakeholders throughout the research process; compares important clinical management options; evaluates the outcomes that are most important to patients; and addresses implementation of the research findings in clinical care environments. 

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This project is supported by grant number R18HS021952 from the Agency for Healthcare Research and Quality. The content of this web page is solely the responsibility of the authors (AADE) and does not necessarily represent the official views of the Agency for Healthcare Research and Quality.