Comparative Effectiveness and Patient-centered Outcomes Research

Comparative Effectiveness Research (CER): 

A type of health care research that compares the results of one approach for managing a disease to the results of other approaches.  CER usually compares two or more types of treatment for the same disease.  CER is designed to inform health care decisions by providing evidence on the effectiveness, benefits, and harms of different treatment options. 

Patient Centered Outcomes Research (PCOR): 

Helps people and their caregivers communicate and make informed health care decisions.  PCOR actively engages patients and key stakeholders throughout the research process; compares important clinical management options; evaluates the outcomes that are most important to patients; and addresses implementation of the research findings in clinical care environments.

AADE Resources and Communications on CER/PCOR

External Links and Resources on CER/PCOR

Articles, webinars, and podcasts provided by AADE.

Resources on CER and PCOR provided by outside organizations.


Email AADE to share your thoughts.


This project is supported by grant number R18HS021952 from the Agency for Healthcare Research and Quality. The content of this web page is solely the responsibility of the authors (AADE) and does not necessarily represent the official views of the Agency for Healthcare Research and Quality. 

In This Section